منابع مشابه
Mutagenic activity of concentrated drinking water samples.
Concentrated drinking water extracts prepared by adsorption onto XAD-2 resin have been tested for their ability to induce chromosome damage in mammalian cells. Extracts prepared from drinking waters derived from upland and lowland sources have been found to induce chromosome aberrations in Chinese hamster ovary (CHO) cells and human lymphocytes in vitro. Although the identity of the compounds r...
متن کاملPresence, introduction and removal of mutagenic activity during the preparation of drinking water in the Netherlands.
A survey of the presence of mutagenic activity in drinking water of 18 cities in the Netherlands revealed that in drinking water of 13 cities mutagenic activity could be demonstrated. The activity was detected in the Ames test after concentrating the organic mutagens with a XAD-4/8 procedure. Dose-related responses were observed with concentrates corresponding to 0.5 to 3.0 liters of drinking w...
متن کاملEvaluation of Genotoxic and Mutagenic Activity of Organic Extracts from Drinking Water Sources
An increasing number of industrial, agricultural and commercial chemicals in the aquatic environment lead to various deleterious effects on organisms, which is becoming a serious global health concern. In this study, the Ames test and SOS/umu test were conducted to investigate the potential genotoxicity and mutagenicity caused by organic extracts from drinking water sources. Organic content of ...
متن کاملContribution of chlorination to the mutagenic activity of drinking water extracts in Salmonella and Chinese hamster ovary cells.
The production of chlorinated by-products through chlorine disinfection of drinking water has been well documented. Natural organic precursors for these chemicals include fulvic and humic acids, the chlorination of which leads to the production of mutagenic compounds. Comparisons of extracts of raw versus treated waters have confirmed that clorination during water treatment produces mutagenic a...
متن کامل3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) and mutagenic activity in Massachusetts drinking water.
There is limited information on the prevalence of the potent mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in U.S. water supplies. We measured MX concentrations and mutagenic activity in tap water samples from 36 surface water systems throughout Massachusetts. We found MX levels much higher (up to 80 ng/L) than previously reported in the United States. We also evaluated the ...
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ژورنال
عنوان ژورنال: American Journal of Public Health
سال: 1980
ISSN: 0090-0036,1541-0048
DOI: 10.2105/ajph.70.3.276